Description

Gamma-Cyclodextrin (Native) – CAS 17465-86-4

Gamma-cyclodextrin (γ-cyclodextrin) is a naturally derived cyclic oligosaccharide composed of eight α-1,4-linked D-glucopyranose units. As the largest of the three native cyclodextrins, gamma cyclodextrin is distinguished by its expanded internal cavity, making it highly effective for encapsulating larger hydrophobic molecules. This unique structural feature allows it to play a critical role in pharmaceutical formulations, diagnostic systems, and advanced biochemical research.

At Michigan Diagnostics LLC, we supply high-purity gamma cyclodextrin CAS 17465-86-4 manufactured under strict quality control standards. Each batch is tested for consistency and performance, ensuring reliability for both research and commercial applications. With fast shipping from Michigan and full documentation including Certificates of Analysis (COA), our gamma cyclodextrin is trusted by laboratories and manufacturers across the United States and globally.

Key Properties of Gamma Cyclodextrin

Gamma cyclodextrin offers several advantages over alpha and beta cyclodextrins due to its larger cavity size and improved solubility profile.

• CAS Number: 17465-86-4
• Structure: Cyclic oligosaccharide (8 glucose units)
• Cavity Diameter: Approximately 7.5–8.3 Å
• Water Solubility: Higher than beta cyclodextrin
• Biocompatibility: Suitable for pharmaceutical and biological use

The larger cavity enables gamma cyclodextrin to form inclusion complexes with molecules that are too large for alpha or beta cyclodextrins, making it a preferred choice for advanced applications requiring higher molecular accommodation.

Pharmaceutical and Drug Delivery Applications

Gamma cyclodextrin is widely used in pharmaceutical development as a solubility enhancer and drug delivery excipient. Many active pharmaceutical ingredients (APIs) suffer from poor water solubility, which can limit bioavailability and therapeutic effectiveness. Gamma cyclodextrin addresses this challenge by forming inclusion complexes that improve solubility, stability, and absorption.

Common pharmaceutical uses include:

• Enhancing solubility of poorly water-soluble drugs
• Stabilizing sensitive or labile compounds
• Reducing drug irritation and toxicity
• Enabling controlled and sustained release formulations
• Supporting delivery of larger or more complex molecules

Because of its favorable safety profile and ability to encapsulate larger molecules, gamma cyclodextrin is increasingly used in modern drug formulation strategies, including oral, injectable, and topical systems.

Biotechnology and Diagnostic Applications

In diagnostic and biochemical settings, gamma cyclodextrin plays an important role in stabilizing reagents and improving assay performance. Its ability to interact with hydrophobic regions of biomolecules helps maintain structural integrity and enhances reproducibility.

Applications include:

• Stabilization of enzymes and proteins
• Improvement of assay signal consistency
• Extension of reagent shelf life
• Use in chemiluminescent and enzymatic assay systems
• Support for high-sensitivity diagnostic workflows

Gamma cyclodextrin is particularly valuable in environments where precision and reliability are critical, such as clinical diagnostics, ELISA development, and advanced research assays.

Food, Cosmetic, and Industrial Uses

Beyond pharmaceutical and diagnostic applications, gamma cyclodextrin is widely used in food science, cosmetics, and industrial formulations due to its ability to encapsulate and protect active ingredients.

These applications include:

• Flavor and fragrance encapsulation
• Odor masking and stabilization
• Nutraceutical delivery systems
• Cosmetic ingredient stabilization
• Protection of volatile or sensitive compounds

Its natural origin and non-toxic profile make gamma cyclodextrin suitable for a wide range of consumer and industrial products.

Why Choose Michigan Diagnostics for Gamma Cyclodextrin

Selecting the right gamma cyclodextrin supplier in the USA is essential for ensuring product quality, regulatory compliance, and consistent supply. Michigan Diagnostics offers a reliable domestic source backed by decades of expertise in biochemical manufacturing.

We provide:

• High-purity gamma cyclodextrin with full COA documentation
• Consistent batch-to-batch quality for reproducible results
• Fast 2–3 day shipping from Michigan
• Technical support for formulation and application questions
• Custom synthesis and bulk supply capabilities

Our manufacturing processes align with global quality standards, supporting both research-grade and industrial-scale applications.

Packaging and Availability

Gamma cyclodextrin (native) is available in a range of packaging sizes to accommodate different use cases, from laboratory research to full-scale production.

Options include:

• Small research quantities
• Pilot-scale batches
• Bulk commercial volumes

Custom packaging and documentation can be provided upon request to meet specific project requirements.

Order Gamma Cyclodextrin CAS 17465-86-4

If you are looking to buy gamma cyclodextrin in the USA, Michigan Diagnostics delivers high-quality material with fast turnaround and dependable support. Whether you are developing pharmaceutical formulations, diagnostic assays, or industrial applications, our team is ready to assist.

Contact us today for pricing, technical specifications, or custom requirements.